To further explore the relationship between TOB1-induced autophagy and exosomes in gastric cancer, the exosomes secreted by gastric cancer cells overexpressing TOB1 (exo-AGS-TOB1) and control gastric cancer cells (exo-AGS-Vector) were cocultured with TOB1-knockout gastric cancer cell line HGC-27-TOB1-6E12 for 48 hours. The gene discussed is TOB1; the disease is gastric cancer.