Next, it was demonstrated that the level of serum TNF-β in patients with AD was positively correlated with the score of MoCA scale, while there exhibited no significant correlation between serum inflammatory factors such as IL-4, IL-6, IL-10, TNF-α, CCL-2, MoCA, and ADAS-cog, which was consistent with previous studies [23]. Here, CCL2 is linked to Alzheimer disease.