It has been reported that the level of serum IL-10 factor in dementia patients is higher compared to healthy controls [23], but another study found that there is no difference in serum IL-10 factor levels among AD patients, vascular dementia patients, PD patients, and healthy controls [21]; so, the relationship between IL-10 and the pathological mechanism of AD patient needs to be further studied. The gene discussed is IL10; the disease is vascular dementia.