As shown in Figure 6, the patients with EBV-HLH had upregulated CRP levels (p = 0.0004), MSN levels (p = 0.0044), LGALS3BP levels (p = 0.0018), and HSPA8 levels (p = 0.0015) and downregulated PLG (p = 0.0007), and FN1 levels (p = 0.021) in the plasma exosomes. This evidence concerns the gene HSPA8 and hemophagocytic syndrome.