PLK1 and lung cancer: Other genes, including PLK1, CDCA8, ANLN, and RACGAP1, were all discovered to play different roles in proliferation, metastasis, and enhanced chemotherapy sensitivity to doxorubicin in lung cancer (De Carcer et al., 2018; Ge et al., 2019; Xu et al., 2019; Hu et al., 2021).