ALKBH3 and Familial prostate cancer: The m1A demethylase ALKBH3, also known as prostate cancer antigen 1 (PCA-1), in addition to being exceptionally abundant in prostate cancer (Konishi et al., 2005), the oncogenic role of m1A demethylation has been found in colon (Zhao et al., 2019), breast (Woo and Chambers, 2019), and lung cancers (Tasaki et al., 2011).