IL6R and prostate neoplasm: The functional characteristics of IL-6 and its specific receptor (IL-6R) determine various biological responses in prostate tumors, probably explained by IL-6's ability to promote pro- and anti-inflammatory responses [7, 8, 23, 24], to interact with a diversity of target cells [10, 25–27], to induce autocrine and paracrine effects in prostate tissue [12, 24, 28], and to activate intracellular signaling pathways (Jak/S) [10];