They found that increased levels of IL-6 and IL-10, neutrophil to lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lactate dehydrogenase (LDH) or reduced absolute lymphocyte count (ALC) and albumin (ALB) levels during ICI treatment may act as biomarkers for the early diagnosis of CIP. Here, IL6 is linked to hereditary sensory and autonomic neuropathy.