Consistent with these results, our pathways analysis with the 98 identified candidate genes revealed a significant enrichment of the DNA packaging (TNP2/PRM1/PRM2/PRM3), TNF-signaling pathway (TRAF5/CREB5/CASP7/CHUK), and toxoplasmosis (TGFβ2/CHUK/CIITA/SOCS1) in the tolerant animals (Figure 3). The gene discussed is CREB5; the disease is toxoplasmosis.