In contrast, polyclonal T-cells had up-regulation of genes related to HTLV-1 infection (NFKBIA and EGR1), cytokine interaction (CCL4 and IL2RG), apoptosis, and inflammatory response, as well as genes down-regulated in angioimmunoblastic T-cell lymphoma (AILT). This evidence concerns the gene EGR1 and angioimmunoblastic T-cell lymphoma.