Additionally, IL-13Rα2 overexpression correlates with advanced disease and poor prognosis in colorectal carcinoma (CRC) (22), gastric cancer (23), breast cancer (24, 25), clear cell ovarian cancer (26), lung cancer (27), ACC (28), papillary thyroid cancer (29), pancreatic ductal adenocarcinoma (30), and glioblastoma (GBM) (31–33). This evidence concerns the gene IL13RA2 and breast cancer.