Interestingly, only in the 180μg group did the levels of NP-specific IFNγ SFC triggered by OVX836 remain above the thresholds of 100 SFC/106 PBMCs (36) for more than 50% of the subjects, a threshold considered as predictive of an efficacy against PCR-confirmed symptomatic influenza in adults using the same assay as the one used in this study. The gene discussed is IFNG; the disease is influenza.