Furthermore, since no significant changes were observed in the expression of hamp2, it is reliable to say that during anemia, in teleost fish, increased erythropoietin and erythroferrone levels only lead to the suppression of hamp1 and have no impact on hamp2 (which further corroborates the mainly antimicrobial role of this type of hepcidin). Here, EPO is linked to anemia (phenotype).