Importantly, we have shown that CCR5+ cells are significantly enriched in all glioblastoma-infiltrating T-cell subsets, and CCR5 ligands were detected in supernatants from dissociated glioblastoma biopsies, implicating a key role for this axis in the infiltration and/or retention of T cells in glioblastoma. This evidence concerns the gene CCR5 and glioblastoma.