Representative histograms for CD4+ T-cell subsets illustrate the typical chemokine receptor expression patterns observed, and demonstrate that staining for CCR2, CCR5, CXCR3 and CXCR6 was robust in glioblastoma-infiltrating T-cell populations compared to matched blood naïve CD4+ T cells (Figure 3A and Supplementary Figure 4). Here, CXCR6 is linked to glioblastoma.