Meanwhile, multiplex immunofluorescence staining was used to verify the expression of CD147 on macrophages and M2 macrophages in these cancers, which CD147 was mainly expressed on CD163+ M2 macrophages in BLCA, LSCC, CESC, PSCC, TGCT, and PRAD. The gene discussed is BSG; the disease is bladder transitional cell carcinoma.