CHGA and telomere syndrome: Figures 6C, D indicate that SPi was the independent prognostic factor for STS. Besides, the difference of stemness between high-SPi and low-SPi patients was assessed using mRNAsi in Figure 6E. High-SPi patients were characterized by high stemness (mRNAsi), which was consistent with a positive correlation between SPi and mRNAsi (cor = 0.24, p = 9.7e-05, Figure 6F). Then, we assessed clinical characteristics of SPi (Figure S5C).