We found that overexpression of Galectin-9 on K562 cells had no impact on T2DM NK cells mediated cytotoxicity and blocking Galectin-9/Tim-3 interaction with antibodies did not affect T2DM NK cells mediated cytotoxicity against K562-Galectin-9 (Figure 7A). Here, HAVCR2 is linked to type 2 diabetes mellitus.