Furthermore, JUN was downregulated in IgAN (p < 0.0001, Fold Change: −3.36), lupus nephritis (p < 0.001, Fold Change: −1.574), and diabetic nephropathy (p < 0.05, Fold Change: −1.873), membranous glomerulonephropathy (p < 0.0001, Fold Change: −1.992), and minimal change disease (p < 0.0001, Fold Change: −2.054) (Figures 8K–O). Here, JUN is linked to diabetic kidney disease.