A previous study suggested that lncRNA HOXA cluster antisense RNA 2 (HOXA-AS2) is downregulated in sepsis patients, CLP mouse models, and LPS-stimulated HK-2 cells while its overexpression alleviates SA-AKI by targeting miR-106b-5p and restrains the Wnt/β-catenin and NF-κB pathways (Wu et al., 2020). The gene discussed is HOXA-AS2; the disease is acute kidney injury.