Results from this study shown that the expression levels for mRNA of spermine anabolic and catabolic enzymes: ornithinedecarboxylase (ODC1), S-adenosylmethionine decarboxylase (AMD1), and antizyme (OAZ1) vary in different cellular components in tissue, and correlate with patient PSA velocities, (Kaul et al., 2010), that may explain the immune-like responses of prostate healthy epithelia in biosynthesis of spermine for inhibitions of cancer growth while located in the prostate. Here, KLK3 is linked to cancer.