The diagnosis of Morvan syndrome was based on the combination of CNS (irritability, fatigue, episodes of crying, and dyssomnia), PNS (pain), and dysautonomia nervous system symptoms (tachycardia, skin rash, hypertension, and profuse sweating) as well as serum LGI1 and CASPR2 antibodies. This evidence concerns the gene LGI1 and hypertensive disorder.