Through the multivariate analyses, we found that age (45–60 years: OR: 5.359; 60–75 years: OR: 15.193; ≥ 75 years: OR = 18.179; all p ≤ 0.001), smoking (OR: 1.651, 95% CI: 1.247–2.184, p < 0.001), an FIB levels (2.5–3.5 g/L: OR: 1.354; ≥ 3.5 g/L: OR: 1.926; all p < 0.05) were positively correlated with cancer, while HGB levels (OR: 0.743, 95% CI: 0.560–0.986, p = 0.040) was negatively related to cancer. Here, CYGB is linked to cancer.