This study also found that cervicitis combined with HPV type infection is significantly negatively and IFN-γ (r = -0.846, P < 0.001); cervicitis combined with HPV type infection is significantly positively correlated with both IL-4 and TNF-α (both P < 0.001); TNF-αis a pleiotropic cytokine, which is mainly secreted by macrophages and is widely involved in the process of cellular reactions. This evidence concerns the gene TNF and cervicitis.