Indeed, LOH2 overexpression (LOH2 A plants) enhanced plant resistance to PsmDG3 infection, but this effect was abrogated by the pad4-1, eds1-2, or sid2-1 mutations (Supplementary Figures 8A,B), indicating that LCF Cer induces plant resistance through PAD4, EDS1, and SA. The gene discussed is PADI4; the disease is infection.