The expression of T-cell immunoglobulin domain and mucin domain-containing molecule 3 (TIM-3) encoded by HAVCR2 in CD4+ and CD8+ T cells of the PCa patients was significantly increased compared with benign prostatic hyperplasia, suggesting that it may affect the development and progression of PCa (75). The gene discussed is HAVCR2; the disease is posterior cortical atrophy.