It can be seen from Figure 4 that the survival analysis of down-regulated genes such as ESR1 and AR, up-regulated genes such as CCNB1, CDK1, AKR1C3 and CCNA2 is statistically significant, suggesting that the above genes may become potential target genes for the survival and prognosis of PADP for the treatment of liver cancer. This evidence concerns the gene AKR1C3 and liver cancer.