This is also supported by the KEGG database analysis (https://www.kegg.jp/), in which growth factors such as EGF, TGF, and HGF promote the expression of CCND1 through Ras–MEK–ERK axis in non-small cell lung cancer (NSCLC) (Supplementary Figure 1). The gene discussed is EGF; the disease is non-small cell lung carcinoma.