Other rare renal tumors with distinct genetic characterizations include ALK rearrangement-associated RCC (ALK-RCC), TCEB1 renal cell carcinoma, renal medullary carcinoma, collecting duct carcinoma, tubulocystic RCC, clear cell papillary RCC, acquired cystic disease-associated RCC, and mucinous tubular spindle cell carcinoma (34). The gene discussed is ALK; the disease is kidney medullary carcinoma.