The value of SRPK1 as a prognostic marker for cancer was recently reviewed by Nikas et al., 2019, and they posit that SRPK1 is indeed a promising prognostic marker for non-small cell lung, breast, prostate, colorectal, stomach, liver, and esophageal cancers based on clinicopathological criteria (58). This evidence concerns the gene SRPK1 and esophageal cancer.