MKNK2 and lung carcinoma: SRSF1 was also found to be a direct target of oncogenic transcription factor MYC in lung carcinomas, and its induction was shown to be responsible for AS of signaling kinase MKNK2 that codes for the eIF4e-kinase Mnk2 and TEAD1 that codes for the transcriptional enhancer factor TEF-1 (33).