Decrease in tumor-infiltrating CD3+ T-cells in patients colonized by CoPECDecrease in CD3+ CD8 T-cells in mice with chronic CoPEC infectionIncrease colonic inflammationDecrease in antitumor T-cells in the mesenteric lymph nodes of CoPEC-infected miceDecrease the anti-PDCD1 immunotherapy efficacy in MC38 tumor model. The gene discussed is PDCD1; the disease is neoplasm.