SELE and inflammatory bowel disease: In some cases, CAMs show elevated plasma levels of their soluble forms in patients suffering from chronic diseases: soluble E-selectin in inflammatory bowel disease, bronchial asthma, atopic dermatitis (10) as well as in hypertension, diabetes, and hyperlipidemia (23); soluble P-selectin in cardiovascular diseases, especially in deep vein thrombosis (24).