With a loose threshold of statistical significance (P < 1.00E − 4), another 17 genes were identified to be associated with epilepsy (BPTF, CAMTA1, SCN9A, SLCO3A1, TTC21B, FAM69A, KIAA0408, KLHDC4, LOC101927250, LOC101929141, PABPC4, POU6F2, PXN, RPL5, SAMD10, USP45, and ZKSCAN3), the former five genes of which were previously verified or published associated genes or regions (Table S1). This evidence concerns the gene USP45 and epilepsy.