According to the criteria, “BC,” “CC,” “DC,” “EC,” “LC,” “NC,” “SC,” and “IC,” the top ten candidate nodes were selected, including CXCL12, IGF1, EGFR, JUN, CXCL2, ESR1, FOS, SAA1, CCL28, and TGFBR2 (Table 1). This evidence concerns the gene CXCL2 and breast cancer.