ESR1 and breast cancer: According to the criteria, “BC,” “CC,” “DC,” “EC,” “LC,” “NC,” “SC,” and “IC,” the top ten candidate nodes were selected, including CXCL12, IGF1, EGFR, JUN, CXCL2, ESR1, FOS, SAA1, CCL28, and TGFBR2 (Table 1).