According to the criteria, “BC,” “CC,” “DC,” “EC,” “LC,” “NC,” “SC,” and “IC,” the top ten candidate nodes were selected, including CXCL12, IGF1, EGFR, JUN, CXCL2, ESR1, FOS, SAA1, CCL28, and TGFBR2 (Table 1). Here, IGF1 is linked to breast cancer.