IL6 and chronic kidney disease: Although it is known that systemic chronic inflammation and increased inflammatory markers such as C-reactive protein (CRP), Interleukin six (IL-6), and Tumor Necrosis Factor-alpha (TNF-α), are presented by ND-CKD patients and yet could increase muscle mass degradation and sarcopenia in this population (5, 9) these findings are still controversial in some researches (3, 7).