In particular, variables are organized to define family history, symptoms and clinical/laboratory signs at disease onset, symptoms developed during patient's history, Still's disease classification criteria (11–15), genetic features (including human leukocyte antigens and genes not related to the most common autoinflammatory diseases, such as CSF1 and IL18, suggested to be associated to Still's disease), comorbidities, cardiovascular risk, detailed information about treatments, including dosage changes, combinations, withdrawals or additions carried out over time. The gene discussed is CSF1; the disease is systemic-onset juvenile idiopathic arthritis.