Recently, much work has been done to explore the association of inflammation, as reflected by C reactive protein (CRP), interleukin-6 (IL-6), and IL-8, with VCZ concentration in transplantation patients, patients with blood diseases, and critically ill patients (van Wanrooy et al., 2014; Vreugdenhil et al., 2018; Gautier-Veyret et al., 2019). This evidence concerns the gene IL6 and blood disease.