Two other recent studies reported a similar phenotype and confirmed that METTL3 is critical for maintaining the malignant phenotypes by targeting lncRNA MEG3/miR-544b/BTG2 and lncRNA NIFK-AS1/miR-637/AKT1 of HCC cells (Chen et al., 2021b; Wu et al., 2021b). Here, NIFK is linked to hepatocellular carcinoma.