A previous study revealed that cinnamaldehyde mediates endoplasmic reticulum stress and autophagic cell death via the PERK-CHOP signaling pathway, the inhibition of G9a binding on Beclin-1 and LC3B promoter, and dissociation of Bcl-2–Beclin-1 in GC cells (Kim, 2022). The gene discussed is EIF2AK3; the disease is gastric cancer.