IL17A and Stroke: Ast can release a large amount of IL-17A after stroke, and at the same time, IL-17AR is also highly expressed, and the transformation of MG to M1 type can be reduced by inhibiting IL-17A derived from Ast, which suggests that the polarization of M1-type microglia may be mediated by the IL-17 signaling and is closely related to Ast (Ronaldson and Davis, 2020).