ALB and chronic kidney disease: In this murine CKD model, FC treatment significantly decreased serum urea nitrogen concentrations (geometric mean (95% CI) 62 (48, 80) vs. 150 (103, 220) mg/dl, p < 0.001 (59% reduction); Fig. 5a); serum creatinine (geometric mean (95% CI) 0.20 (0.15, 0.25) vs. 0.50 (0.38, 0.66) mg/dl, p < 0.001 (60% reduction); Fig. 5b); serum creatinine normalized to body weight (Fig. 5c); and the urine albumin-to-creatinine ratio (geometric mean (95% CI) 112 (96, 131) vs. 188 (138, 255) mg/g, p = 0.005 (40% reduction); Fig. 5d).