Compared with the DM or DM + Sh-NC group, the DM + ShPin1 or DM + JQ1-group tumor tissues exhibited reduced positivity for BRD4, NAP1L1, PCNA, and MMP9, and increased positivity for P21, while JQ1 treatment had no effect on Pin1 expression (Fig. 5i). The gene discussed is PCNA; the disease is neoplasm.