To further clarify the mechanisms of seRNA LOC100506178 regulating NPC metastasis, RNA pull-down-MS was used to explore LOC100506178-binding proteins: ILF3, ROA2, hnRNPK, SRSF1, and YBOX3 (Fig. 5A; Supplementary Data 6). This evidence concerns the gene HNRNPK and nasopharyngeal carcinoma.