HnRNPK occupied the promoter of MICAL2, but LOC100506178 did not bind with MICAL2, demonstrating that seRNA LOC100506178 recruited local hnRNPK to indirectly modulate the expression of MICAL2 and EMT genes, subsequently boosting EMT in NPC metastasis. The gene discussed is MICAL2; the disease is nasopharyngeal carcinoma.