PIEZO1 and hepatocellular carcinoma: After the upregulated expression level of Piezo1 in HCC was determined, we further verified the expression difference through the analyses of mRNA datasets from TCGA (P = 0.0004) and Gene Expression Omnibus (Fig. 2A, GSE76297 P = 0.0364, GSE36376 P < 0.0001, GSE10143 P < 0.0001), which verified our experiments that Piezo1 upregulated in HCC.