Consistent with the hepatic steatosis, WT-EB mice exhibited elevated plasma ALT levels compared to WT-CB mice, indicative of liver damage and injury, while KO-EB mice displayed lower plasma ALT levels than those of WT-EB mice (Fig. 1E), demonstrating that miR-141/200c deficiency ameliorates ethanol induced liver injury. The gene discussed is GPT; the disease is fatty liver disease.