GPX4 and congenital rubella syndrome: Concerning Gpx4, we found a two-way ANOVA significant effect of the previous conditions (F2, 51 = 5.999; P = 0.0046), with increased levels of this enzyme only in animals exposed to chronic stress and treated with lurasidone (CRS/LUR: + 29% vs. CRS, P < 0.05; Fig. 3d).