AIFM2 and cancer: Analyses of NRF2 chromatin immunoprecipitation coupled with high-throughput sequencing (ChIP-seq) datasets from GEO revealed a strong binding of NRF2 on the FSP1/AIFM2 promoter in diverse cancer cell lines (Supplementary Fig. 4a, b; note that FSP1 transcription is directed from the right to the left as indicated by the arrow).