RARRES2 and glioblastoma: Interestingly, rChemerin treatment did not change the mesenchymal status of GSC40 cells, which already had abundant mesenchymal features and chemerin expression (Supplementary Fig. S2G), highlighting the limitation of its pro-mesenchymal effect on high chemerin-expressing GBM cells with high mesenchymal features (Supplementary Fig. S3A, B).