In fact, type I interferons have been shown to induce CXCL10 and CXCL9 production in DCs and subsequently enhance their ability to stimulate CD8 +effector T cells.59 60 However, other IFN-modulated chemokines/cytokines couple be involved, potentially in a different manner in the tumor or LN.61–64 Thus, further exploration on how other chemokines/cytokines may be impacted by Alb-IFNβ should be considered. The gene discussed is ALB; the disease is neoplasm.