We first depleted either CD4 +or CD8+T cells in TC-1 tumor-bearing mice (n=5) by injecting them with either 200 μg of anti-mouse CD4 antibodies or 100 μg of anti-mouse CD8 antibodies daily for 3 days, followed by Alb-IFNβ and E7 vaccination (figure 6A). Here, CD4 is linked to neoplasm.