IFNB1 and neoplasm: To understand how Alb-IFNβ affects antigen-specific CD8 +T cells trafficking to the tumor microenvironment (TME), tumor-bearing mice were treated with either Alb-IFNβ, IFNβ, or PBS control followed by adaptive transfer of luciferase-expressing E7-specific CD8 +T cells (see online supplemental figure 3).