IFNB1 and neoplasm: Previous studies have also suggested that due to the circulation pattern of albumin in the plasma, albumin fusion proteins are able to preferentially traffic toward the draining LNs.15 16 From our experiments, we found that Alb-IFNβ was present at higher levels in LNs (figure 2B), and targets to both the tumors and the tumor draining LNs (tdLNs) more efficiently than IFNβ alone (figure 2C).