IFNB1 and neoplasm: Additionally, Alb-IFNβ was able to induce higher DC activation in the tdLNs compared with IFNβ (online supplemental figure 4D).Thus, our experiments showed that Alb-IFNβ treatment successfully increases chemokine expression, which also increases CD8 +T cell activity and DC maturation in the tdLNs of tumor bearing mice.