Moreover, H1299 tumors that developed in the presence of Ago2 overexpression alone or with TAp63 exhibited much less neovascularization than the control H1299 tumors, while H1299 tumors that developed in the presence of Ago2 and ΔNp63 manifested higher vascular density and larger tumor size (Supplementary Fig. 4G). Here, AGO2 is linked to neoplasm.