On day 24 after treatment, mice treated with 5voHSV2 had an average tumor volume of 362 mm3, while the average tumor volume of mice inoculated with OVs was 1 450 mm3 (oHSV2-IL12), 1 711 mm3 (oHSV2-PD1v), 951 mm3 (oHSV2-IL7 × CCL19), 893 mm3 (oHSV2-GM-CSF) and 1 443 mm3 (oHSV2-IL15). Here, CSF2 is linked to neoplasm.