CD8A and neoplasm: Furthermore, in the ADT model, Tc17 cells reduced tumor growth as well as enhanced tumor infiltration of CXCL10+ MoDCs and CD8+ T cells (Fig. 8d), suggesting that the antitumor effect of Tc17 in vivo was not only from a direct cytotoxic killing effect of Tc17, but also from the recruitment of CD8 + T cells.